Women and Heart Failure: The Ongoing Challenges in Cardiovascular Clinical Trials

Tuesday, 15 October 2024, 10:53

Heart failure remains a critical issue, yet women's representation in cardiovascular clinical trials continues to lag behind men. Despite historical underrepresentation, progress has been made, yet significant gaps persist. This post explores these disparities and the implications for women's heart health in clinical research.
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Women and Heart Failure: The Ongoing Challenges in Cardiovascular Clinical Trials

The Challenge of Heart Failure Disparities in Women

Heart failure poses a significant risk to women, yet they are consistently underrepresented in cardiovascular clinical trials. Although advancements have been made since the 1990s, in 2024, women still constitute only 26% of participants in heart failure trials.

Clinical Trial Enrollment: The Gender Gap

A detailed review of studies reveals not just the numbers, but the systemic barriers to women's participation in research. The complexity of recruiting women is heightened by various factors, including lack of awareness, logistical hurdles, and differences in risk perception.

  • Women face more challenges in accessing trial centers and often lack support for transportation and childcare.
  • Perceptions of higher risk associated with trial participation deter many women.
  • Women require more time and external validation before making health-related decisions.

Path Forward: Closing the Gap

Experts recommend a comprehensive approach to ensuring inclusive research practices. This encompasses addressing barriers at multiple levels, educating healthcare providers, and empowering women to advocate for their health.


This article was prepared using information from open sources in accordance with the principles of Ethical Policy. The editorial team is not responsible for absolute accuracy, as it relies on data from the sources referenced.


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