Terns Pharmaceuticals Reports Positive Phase 1 Trial for TERN-601 in Obesity Treatment

Monday, 9 September 2024, 04:05

Terns Pharmaceuticals has announced positive Phase 1 clinical trial results for TERN-601, a once-daily oral GLP-1R agonist aimed at obesity treatment. This trial revealed a clinically significant mean weight loss of up to 5.5% over 28 days, highlighting the potential of TERN-601 in obesity management. Importantly, the treatment was well-tolerated without any notable dose interruptions or reductions.
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Terns Pharmaceuticals Reports Positive Phase 1 Trial for TERN-601 in Obesity Treatment

Overview of TERN-601

Terns Pharmaceuticals has initiated a breakthrough with their latest development, TERN-601. This once-daily oral GLP-1 receptor agonist has shown promising results in recent clinical trials.

Clinical Trial Findings

The Phase 1 clinical trial outcomes demonstrated statistical significance, leading to a mean weight loss of up to 5.5% over a short period of just 28 days. Notably, the placebo-adjusted weight loss reached 4.9%. This finding emphasizes the potential of TERN-601 as a viable treatment for obesity.

Safety and Tolerability

  • Well-tolerated with no treatment-related dose interruptions.
  • No significant reductions or discontinuations were reported.

Implications for Obesity Treatment

The findings from Terns Pharmaceuticals pave the way for potential interventions in obesity management. TERN-601 may represent a new frontier for patients seeking effective weight management solutions.


This article was prepared using information from open sources in accordance with the principles of Ethical Policy. The editorial team is not responsible for absolute accuracy, as it relies on data from the sources referenced.


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