Periodontal Disease and Rheumatoid Arthritis: The Link Between Bacterial Biofilm and Systemic Diseases
Understanding the Connection Between Periodontal Disease and Systemic Diseases
Recent studies reveal a concerning link between periodontal disease and rheumatoid arthritis. The presence of A. actinomycetemcomitans, a pathogen associated with gum infections, may worsen arthritis symptoms through inflammatory pathways.
Bacterial Biofilms and Inflammasome Activation
Bacterial biofilms form a protective barrier that enhances the survival of periodontal pathogens. This results in the activation of inflammatory pathways, including inflammasome activation, which contributes to the systemic inflammatory response seen in rheumatoid arthritis.
Implications for Treatment and Prevention
Recognizing the impact of gum infections on systemic diseases underscores the need for effective dental care. Addressing oral health can potentially mitigate the progression of rheumatoid arthritis and related conditions.
This article was prepared using information from open sources in accordance with the principles of Ethical Policy. The editorial team is not responsible for absolute accuracy, as it relies on data from the sources referenced.