GLP-1 Drugs and the Impact of Discontinuation on Weight Management

Thursday, 26 September 2024, 13:02
GLP-1 drugs have shown significant effects on weight loss, but evidence reveals patients often regain weight after stopping these medications. Studies highlight that weight regain is a common issue for individuals on GLP-1 treatments like Semaglutide. Understanding these dynamics is crucial as patients seek effective weight management solutions.
Medpagetoday
GLP-1 Drugs and the Impact of Discontinuation on Weight Management

Understanding the Weight Regain After Discontinuation of GLP-1 Drugs

Recent studies demonstrate that many patients experience weight regain after stopping GLP-1 drugs. The STEP 1 trial extension examined patients taking weekly semaglutide 2.4 mg (Wegovy) and observed a noticeable pattern of weight regain following discontinuation.

Key Findings

  • Most participants reverted to pre-treatment weight after discontinuation.
  • Maintaining lifestyle changes alongside medication use may help mitigate weight regain.

Clinical Implications

Healthcare providers should inform patients about the potential for weight regain after stopping GLP-1 medications, emphasizing the importance of ongoing lifestyle modifications to support lasting weight loss.

This article was prepared using information from open sources in accordance with the principles of Ethical Policy. The editorial team is not responsible for absolute accuracy, as it relies on data from the sources referenced.

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