Understanding Epigenetics: The Role of Epigenetics in Human Disease
Exploring Epigenetics in Disease
Epigenetics plays a vital role in shaping human health by regulating gene expression without altering the underlying DNA sequence. Through modifications to chromatin, epigenetic markers can activate or silence genes, impacting cellular function and health outcomes. Various factors, including environmental influences, can induce these epigenetic changes, potentially leading to diseases such as cancer, cardiovascular issues, and neurological disorders.
Key Mechanisms of Epigenetics
- DNA Methylation: This process modifies DNA and can inhibit gene transcription.
- Histone Modification: Changes to histones can alter chromatin accessibility, affecting gene expression.
- Non-coding RNAs: These RNA molecules can regulate gene activity through various mechanisms.
Chronic stress is also linked to detrimental epigenetic alterations, potentially exacerbating health issues.
This article was prepared using information from open sources in accordance with the principles of Ethical Policy. The editorial team is not responsible for absolute accuracy, as it relies on data from the sources referenced.