Discovering cGAS-STING and Its Role in the Immune System: 2024 Lasker Award Announcement
cGAS-STING and the Immune System
The discovery of cGAS, an enzyme that detects DNA-based threats, has led to significant advancements in immunology. Zhijian 'James' Chen's groundbreaking work in signaling pathways has revealed how the immune system responds to these threats effectively. The enzyme communicates threats to the immune system, enhancing its ability to combat various diseases.
The 2024 Lasker Award
The Lasker Award, presented by the Lasker Foundation, recognizes significant contributions to medical science. This year, the award honors Zhijian Chen for his pivotal role in uncovering how cGAS interacts with the STING pathway, a discovery that enhances our understanding of the immune system's innate responses.
Importance of Signaling Molecules
- Signaling Molecules are critical in the activation of the immune response.
- The cGAS-STING pathway highlights key interactions in the detection of pathogens.
- Research into this pathway may facilitate new therapeutic approaches for autoimmune diseases and cancers.
This article was prepared using information from open sources in accordance with the principles of Ethical Policy. The editorial team is not responsible for absolute accuracy, as it relies on data from the sources referenced.