Athira Pharma's Shift Towards ALS Drug Development After Alzheimer's Drug Failure

Wednesday, 18 September 2024, 05:14

ALS drug development has become the focal point for Athira Pharma after the failure of its Alzheimer’s drug, fosgonimeton. The company plans to concentrate resources on ATH-1105 and has made significant workforce reductions to streamline efforts. This shift marks a new chapter in Athira's journey in the biotech landscape.
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Athira Pharma's Shift Towards ALS Drug Development After Alzheimer's Drug Failure

Understanding Athira Pharma's Strategic Shift

Athira Pharma is now redirecting its focus to ALS drug development following the disappointing results of its Alzheimer’s medication, fostgonimeton. The company will invest in the advancement of ATH-1105, recognizing the critical need for effective treatments in the ALS community.

Challenges Faced in Alzheimer’s Drug Development

  • The Alzheimer’s drug was unable to meet the primary endpoints outlined in the LIFT-AD trial.
  • Athira's decision comes as part of a broader strategic plan to minimize costs.
  • The workforce reduction by 70% will help the company save an estimated $13.4 million.

Future Directions in ALS Drug Development

With the new commitment to ALS, Athira aims to leverage its resources towards discovering and developing therapies that address this devastating disease. Stay tuned for updates on their progress.


This article was prepared using information from open sources in accordance with the principles of Ethical Policy. The editorial team is not responsible for absolute accuracy, as it relies on data from the sources referenced.


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