Neurocrine Ends Luvadaxistat Development Following Disappointing Cognitive Study

Thursday, 12 September 2024, 13:58

Neurocrine has halted the development of luvadaxistat after disappointing results in a Phase 2 cognitive study for schizophrenia. This decision reflects a significant setback in potential treatment options for cognitive impairment associated with schizophrenia. The failed study raises concerns over the efficacy of this drug, emphasizing the challenges in drug development for mental health disorders.
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Neurocrine Ends Luvadaxistat Development Following Disappointing Cognitive Study

Neurocrine Concludes Luvadaxistat Development

Neurocrine Biosciences (NASDAQ:NBIX) has officially ceased development of luvadaxistat after receiving unfavorable outcomes from a Phase 2 clinical trial. This trial was focused on evaluating the drug's effectiveness in treating cognitive impairment in schizophrenia patients.

The Disappointing Study Findings

The recent Phase 2 study did not meet its primary endpoints, leading to the conclusion that further development of luvadaxistat would not be pursued. Participants reported inadequate improvements in cognitive function, prompting Neurocrine's strategic decision to halt the program.

Implications for Mental Health Treatment

The cessation of luvadaxistat development poses critical implications for the treatment landscape of schizophrenia. Notably, cognitive impairment is a disabling component of this mental health condition, affecting numerous individuals. Neurocrine's decision also highlights the ongoing challenges faced by pharmaceutical companies in delivering effective therapies for mental health disorders.

For more details on this study and its impact, please visit the source.


This article was prepared using information from open sources in accordance with the principles of Ethical Policy. The editorial team is not responsible for absolute accuracy, as it relies on data from the sources referenced.


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