Nasal Spray Innovation Targets Respiratory Viruses: Flu, COVID-19, and More
Nasal Spray Combatting Viruses
A nasal spray may serve as a revolutionary approach in the fight against respiratory infections such as flu and COVID-19. Scientists at Brigham and Women’s Hospital have explored a non-drug formulation to potentially outperform conventional masks in blocking infections.
Mechanism of Action
- Pathogen Capture and Neutralizing Spray (PCANS) utilizes a gel-like matrix.
- This spray traps respiratory droplets, immobilizes germs, and neutralizes them, thereby preventing infection.
Lab and Animal Testing
Using a 3D-printed human nose model, researchers found that PCANS captured twice as many droplets compared to natural mucus. “The spray exhibited the ability to block almost 100% of tested viruses,” lead researcher John Joseph noted.
Potential for Human Use
Currently, PCANS is set for further investigation in human clinical trials, opening the door for its use as an alternative to masks against respiratory infections.
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