Understanding Alzheimer’s Disease and Its Impact on Cognitive Function

Thursday, 19 September 2024, 22:01

Alzheimer’s disease is a complex condition characterized by amyloid-β and tau proteins that disrupt brain activity. This article explores how these pathologies contribute to cognitive decline. Research highlights the importance of imaging techniques in understanding neurophysiology and cortical changes associated with dementia in older adults.
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Understanding Alzheimer’s Disease and Its Impact on Cognitive Function

The Role of Amyloid-β and Tau in Alzheimer's Disease

Amyloid-β and tau are two critical proteins involved in Alzheimer’s disease pathology. These proteins interact to create hyperactivity in brain neurons, leading to alterations in cognitive function.

Imaging Techniques and Neurophysiology

  • Advanced imaging provides insights into the cortex's changes.
  • Research shows frequency patterns of brain activity affected by amyloid-β.
  • Understanding neurophysiology can aid in early detection of Alzheimer's.

Pathological Changes and Cognitive Decline

The disruption caused by amyloid-β and tau results in significant impacts on cognitive health:

  1. Cognitive function diminishes as dementia progresses.
  2. Neurotransmitter imbalances due to neuronal changes.
  3. Engagement in regular mental exercises may mitigate some decline.

Continued research into these interactions is essential for developing interventions aimed at preserving brain function in at-risk populations.


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This article was prepared using information from open sources in accordance with the principles of Ethical Policy. The editorial team is not responsible for absolute accuracy, as it relies on data from the sources referenced.


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