Ophthalmology Times: Key Insights from Retina Society 2024 on ONL-1204 for Rhegmatogenous Retinal Detachment

Saturday, 14 September 2024, 09:00

Ophthalmology Times covers the Retina Society 2024's discussion on the promising phase 2 clinical trial results for ONL-1204 aimed at treating rhegmatogenous retinal detachment. The trial highlights significant potential benefits for patients facing vision loss. Key takeaways emphasize the need for enhanced treatment options.
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Ophthalmology Times: Key Insights from Retina Society 2024 on ONL-1204 for Rhegmatogenous Retinal Detachment

Ophthalmology Times: Retina Society 2024 Highlights

Ophthalmology Times provides a comprehensive overview of the recent findings presented at the Retina Society meeting concerning the first-time phase 2 trial results for ONL-1204, a novel treatment for rhegmatogenous retinal detachment.

Key Findings

Durga Borkar, MD, shared crucial insights into how ONL-1204 works by targeting the FAS receptor. This is particularly essential as patients with rhegmatogenous retinal detachment can suffer from significant vision loss even with timely surgical intervention.

  • ONL-1204 showed promise in improving outcomes for high-risk patients, especially those with prolonged macula off status.
  • The study involved two dosage groups, revealing essential data on visual benefits.
  • Follow-up treated patients for 6 months to assess long-term implications.

Future Prospects

Borkar noted the need for improved visual outcomes in patients with rhegmatogenous retinal detachment, indicating plans for further subgroup analyses and meetings with the FDA.


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