Conduit Pharmaceuticals and AstraZeneca Partner on HK-4 Glucokinase Activators for Autoimmune Conditions

Friday, 9 August 2024, 16:18

Conduit Pharmaceuticals has entered into an exclusive license agreement with AstraZeneca, granting the latter rights to key glucokinase activators AZD1656 and AZD5658 aimed at treating autoimmune disorders, as well as the myeloperoxidase inhibitor AZD5904 which targets idiopathic male infertility. Both compounds have demonstrated promising results in preclinical studies and Phase I trials. As Conduit prepares to move forward into Phase II clinical trials, this collaboration underscores its commitment to advancing innovative therapies in the pharmaceutical landscape.
Yahoo Finance
Conduit Pharmaceuticals and AstraZeneca Partner on HK-4 Glucokinase Activators for Autoimmune Conditions

Conduit Pharmaceuticals and AstraZeneca Collaboration

Conduit Pharmaceuticals Inc. has announced a significant partnership with AstraZeneca through an exclusive license agreement.

Details of the Agreement

  • Licensed Products: HK-4 Glucokinase activators AZD1656 and AZD5658
  • Target Indications: Autoimmune diseases and idiopathic male infertility

Clinical Developments

  1. Preclinical Studies: Positive results have been observed.
  2. Phase I Trials: Both products showed favorable outcomes.
  3. Next Steps: Initiation of Phase II clinical trials is planned.

Conclusion

This collaboration between Conduit Pharmaceuticals and AstraZeneca is expected to pave the way for groundbreaking treatments in autoimmune conditions and male infertility, potentially impacting the future of pharmaceutical advancements.


This article was prepared using information from open sources in accordance with the principles of Ethical Policy. The editorial team is not responsible for absolute accuracy, as it relies on data from the sources referenced.


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